The Molecular Analysis for Therapy Choice (NCI-MATCH) Trial: Lessons for Genomic Trial Design

BACKGROUND: The proportion of tumors of various histologies that may respond to drugs targeted to molecular alterations is unknown. NCI-MATCH, a collaboration between ECOG-ACRIN Cancer Research Group and the National Cancer Institute, was initiated to find efficacy signals by matching patients with...

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Autores principales: Flaherty, Keith T, Gray, Robert, Chen, Alice, Li, Shuli, Patton, David, Hamilton, Stanley R, Williams, Paul M, Mitchell, Edith P, Iafrate, A John, Sklar, Jeffrey, Harris, Lyndsay N, McShane, Lisa M, Rubinstein, Larry V, Sims, David J, Routbort, Mark, Coffey, Brent, Fu, Tony, Zwiebel, James A, Little, Richard F, Marinucci, Donna, Catalano, Robert, Magnan, Rick, Kibbe, Warren, Weil, Carol, Tricoli, James V, Alexander, Brian, Kumar, Shaji, Schwartz, Gary K, Meric-Bernstam, Funda, Lih, Chih-Jian, McCaskill-Stevens, Worta, Caimi, Paolo, Takebe, Naoko, Datta, Vivekananda, Arteaga, Carlos L, Abrams, Jeffrey S, Comis, Robert, O’Dwyer, Peter J, Conley, Barbara A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566320/
https://www.ncbi.nlm.nih.gov/pubmed/31922567
http://dx.doi.org/10.1093/jnci/djz245

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