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Beyond the Superficial: Disseminated Trichophyton rubrum Infection in a Kidney Transplant Recipient
Superficial dermatophyte infections are common in the general population and are readily treated with topical antifungals. Deeper invasion is rare, and dissemination to visceral organs is extremely uncommon. We describe a 66-year-old renal transplant recipient who developed disseminated Trichophyton...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566364/ https://www.ncbi.nlm.nih.gov/pubmed/33094122 http://dx.doi.org/10.1093/ofid/ofaa281 |
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author | Trottier, Caitlin A Jhaveri, Vimal V Zimarowski, Mary Jane Blair, Barbra M Alonso, Carolyn D |
author_facet | Trottier, Caitlin A Jhaveri, Vimal V Zimarowski, Mary Jane Blair, Barbra M Alonso, Carolyn D |
author_sort | Trottier, Caitlin A |
collection | PubMed |
description | Superficial dermatophyte infections are common in the general population and are readily treated with topical antifungals. Deeper invasion is rare, and dissemination to visceral organs is extremely uncommon. We describe a 66-year-old renal transplant recipient who developed disseminated Trichophyton rubrum infection while undergoing treatment for acute humoral rejection. The infection presented as a facial rash with subsequent dissemination to the lungs and chest wall. All sites of infection improved with combination administration of oral posaconazole and terbinafine. In this work, we review the available literature regarding management of disseminated Trichophyton infection and discuss therapeutic interventions for disseminated dermatophytosis in immunosuppressed hosts. |
format | Online Article Text |
id | pubmed-7566364 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-75663642020-10-21 Beyond the Superficial: Disseminated Trichophyton rubrum Infection in a Kidney Transplant Recipient Trottier, Caitlin A Jhaveri, Vimal V Zimarowski, Mary Jane Blair, Barbra M Alonso, Carolyn D Open Forum Infect Dis Novel Id Cases Superficial dermatophyte infections are common in the general population and are readily treated with topical antifungals. Deeper invasion is rare, and dissemination to visceral organs is extremely uncommon. We describe a 66-year-old renal transplant recipient who developed disseminated Trichophyton rubrum infection while undergoing treatment for acute humoral rejection. The infection presented as a facial rash with subsequent dissemination to the lungs and chest wall. All sites of infection improved with combination administration of oral posaconazole and terbinafine. In this work, we review the available literature regarding management of disseminated Trichophyton infection and discuss therapeutic interventions for disseminated dermatophytosis in immunosuppressed hosts. Oxford University Press 2020-07-05 /pmc/articles/PMC7566364/ /pubmed/33094122 http://dx.doi.org/10.1093/ofid/ofaa281 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Novel Id Cases Trottier, Caitlin A Jhaveri, Vimal V Zimarowski, Mary Jane Blair, Barbra M Alonso, Carolyn D Beyond the Superficial: Disseminated Trichophyton rubrum Infection in a Kidney Transplant Recipient |
title | Beyond the Superficial: Disseminated Trichophyton rubrum Infection in a Kidney Transplant Recipient |
title_full | Beyond the Superficial: Disseminated Trichophyton rubrum Infection in a Kidney Transplant Recipient |
title_fullStr | Beyond the Superficial: Disseminated Trichophyton rubrum Infection in a Kidney Transplant Recipient |
title_full_unstemmed | Beyond the Superficial: Disseminated Trichophyton rubrum Infection in a Kidney Transplant Recipient |
title_short | Beyond the Superficial: Disseminated Trichophyton rubrum Infection in a Kidney Transplant Recipient |
title_sort | beyond the superficial: disseminated trichophyton rubrum infection in a kidney transplant recipient |
topic | Novel Id Cases |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566364/ https://www.ncbi.nlm.nih.gov/pubmed/33094122 http://dx.doi.org/10.1093/ofid/ofaa281 |
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