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Hepatic stem cell Numb gene is a potential target of Huang Qi Decoction against cholestatic liver fibrosis

Numb is a negative regulator of Notch signal pathway. Previous study has demonstrated that Notch signal pathway activation is required for hepatic progenitor cell (HPC) differentiating into cholangiocytes in cholestatic liver fibrosis (CLF), and Huang Qi Decoction (HQD) could prevent CLF through inh...

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Detalles Bibliográficos
Autores principales:	Xu, Wen, Xu, Yan-nan, Zhang, Xu, Xu, Ying, Jian, Xun, Chen, Jia-mei, Chen, Gao-feng, Zhang, Hua, Liu, Ping, Mu, Yong-ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566460/ https://www.ncbi.nlm.nih.gov/pubmed/33060633 http://dx.doi.org/10.1038/s41598-020-74324-1

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