Elevated DHODH expression promotes cell proliferation via stabilizing β-catenin in esophageal squamous cell carcinoma

As a key enzyme in de novo pyrimidine biosynthesis, the expression level of dihydroorotate dehydrogenase (DHODH) has been reported to be elevated in various types of malignant tumors and its tumor-promoting effect was considered to relate to its pyrimidine synthesis function. Here, we revealed one i...

Descripción completa

Detalles Bibliográficos
Autores principales: Qian, Yu, Liang, Xiao, Kong, Pengzhou, Cheng, Yikun, Cui, Heyang, Yan, Ting, Wang, Jinghao, Zhang, Ling, Liu, Yiqian, Guo, Shiping, Cheng, Xiaolong, Cui, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566478/
https://www.ncbi.nlm.nih.gov/pubmed/33060568
http://dx.doi.org/10.1038/s41419-020-03044-1

Ejemplares similares

Ejemplares similares