A genome-wide analysis of Escherichia coli responses to fosfomycin using TraDIS-Xpress reveals novel roles for phosphonate degradation and phosphate transport systems

BACKGROUND: Fosfomycin is an antibiotic that has seen a revival in use due to its unique mechanism of action and efficacy against isolates resistant to many other antibiotics. In Escherichia coli, fosfomycin often selects for loss-of-function mutations within the genes encoding the sugar importers,...

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Detalles Bibliográficos
Autores principales: Turner, A Keith, Yasir, Muhammad, Bastkowski, Sarah, Telatin, Andrea, Page, Andrew J, Charles, Ian G, Webber, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566553/
https://www.ncbi.nlm.nih.gov/pubmed/32756955
http://dx.doi.org/10.1093/jac/dkaa296

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