Cargando…
Gut Microbiome Alters the Activity of Liver Cytochromes P450 in Mice With Sex-Dependent Differences
Sexual differences and the composition/function of the gut microbiome are not considered the most important players in the drug metabolism field; however, from the recent data it is obvious that they may significantly affect the response of the patient to therapy. Here, we evaluated the effect of mi...
Autores principales: | Jourová, Lenka, Vavreckova, Marketa, Zemanova, Nina, Anzenbacher, Pavel, Langova, Katerina, Hermanova, Petra, Hudcovic, Tomas, Anzenbacherova, Eva |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566554/ https://www.ncbi.nlm.nih.gov/pubmed/33123003 http://dx.doi.org/10.3389/fphar.2020.01303 |
Ejemplares similares
-
Gut microbiome affects the metabolism of metronidazole in mice through regulation of hepatic cytochromes P450 expression
por: Zemanová, Nina, et al.
Publicado: (2021) -
The role of the microbiome and psychosocial stress in the expression and activity of drug metabolizing enzymes in mice
por: Zemanová, Nina, et al.
Publicado: (2020) -
Effect of DSS-Induced Ulcerative Colitis and Butyrate on the Cytochrome P450 2A5: Contribution of the Microbiome
por: Satka, Stefan, et al.
Publicado: (2022) -
Butyrate Treatment of DSS-Induced Ulcerative Colitis Affects the Hepatic Drug Metabolism in Mice
por: Jourova, Lenka, et al.
Publicado: (2022) -
Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs
por: Soucek, Pavel, et al.
Publicado: (2001)