Cyclase-associated protein 2 dimerization regulates cofilin in synaptic plasticity and Alzheimer's disease

Regulation of actin cytoskeleton dynamics in dendritic spines is crucial for learning and memory formation. Hence, defects in the actin cytoskeleton pathways are a biological trait of several brain diseases, including Alzheimer's disease. Here, we describe a novel synaptic mechanism governed by...

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Detalles Bibliográficos
Autores principales: Pelucchi, Silvia, Vandermeulen, Lina, Pizzamiglio, Lara, Aksan, Bahar, Yan, Jing, Konietzny, Anja, Bonomi, Elisa, Borroni, Barbara, Padovani, Alessandro, Rust, Marco B, Di Marino, Daniele, Mikhaylova, Marina, Mauceri, Daniela, Antonucci, Flavia, Edefonti, Valeria, Gardoni, Fabrizio, Di Luca, Monica, Marcello, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566557/
https://www.ncbi.nlm.nih.gov/pubmed/33094279
http://dx.doi.org/10.1093/braincomms/fcaa086

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