Cargando…

Cell-free DNA in plasma as an essential immune system regulator

The cell-free DNA (cfDNA) is always present in plasma, and it is biomarker of growing interest in prenatal diagnostics as well as in oncology and transplantology for therapy efficiency monitoring. But does this cfDNA have a physiological role? Here we show that cfDNA presence and clearance in plasma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Korabecna, M., Zinkova, A., Brynychova, I., Chylikova, B., Prikryl, P., Sedova, L., Neuzil, P., Seda, O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566599/ https://www.ncbi.nlm.nih.gov/pubmed/33060738 http://dx.doi.org/10.1038/s41598-020-74288-2

Ejemplares similares

Cell-free DNA from human plasma and serum differs in content of telomeric sequences and its ability to promote immune response
por: Zinkova, Alzbeta, et al.
Publicado: (2017)

Genome-wide miRNA profiling in plasma of pregnant women with down syndrome fetuses
por: Zedníková, Iveta, et al.
Publicado: (2020)

Maternal High-Sucrose Diet Affects Phenotype Outcome in Adult Male Offspring: Role of Zbtb16
por: Školníková, Elena, et al.
Publicado: (2020)

Improving structural variant clustering to reduce the negative effect of the breakpoint uncertainty problem
por: Geryk, Jan, et al.
Publicado: (2021)

Heterozygous connexin 50 mutation affects metabolic syndrome attributes in spontaneously hypertensive rat
por: Šeda, Ondřej, et al.
Publicado: (2016)

Hepatic Gene Expression Profiles Differentiate Steatotic and Non-steatotic Grafts in Liver Transplant Recipients
por: Šeda, Ondrej, et al.
Publicado: (2019)

A member of the Whirly family is a multifunctional RNA- and DNA-binding protein that is essential for chloroplast biogenesis
por: Prikryl, Jana, et al.
Publicado: (2008)

PCR past, present and future
por: Zhu, Hanliang, et al.
Publicado: (2020)

The vision of point-of-care PCR tests for the COVID-19 pandemic and beyond
por: Zhu, Hanliang, et al.
Publicado: (2020)

Detection of cell-free foetal DNA fraction in female-foetus bearing pregnancies using X-chromosomal insertion/deletion polymorphisms examined by digital droplet PCR
por: Zednikova, Iveta, et al.
Publicado: (2020)

Temperature non-uniformity detection on dPCR chips and temperature sensor calibration
por: Gaňová, Martina, et al.
Publicado: (2022)

Analysis of microRNAs in Small Urinary Extracellular Vesicles and Their Potential Roles in Pathogenesis of Renal ANCA-Associated Vasculitis
por: Frydlova, Jana, et al.
Publicado: (2022)

Monitoring of telomere dynamics in peripheral blood leukocytes in relation to colorectal cancer patients’ outcomes
por: Tomasova, Kristyna, et al.
Publicado: (2022)

Ellagic Acid Affects Metabolic and Transcriptomic Profiles and Attenuates Features of Metabolic Syndrome in Adult Male Rats
por: Kábelová, Adéla, et al.
Publicado: (2021)

Quercetin supplementation alters adipose tissue and hepatic transcriptomes and ameliorates adiposity, dyslipidemia, and glucose intolerance in adult male rats
por: Kábelová, Adéla, et al.
Publicado: (2022)

Determination of Advantages and Limitations of qPCR Duplexing in a Single Fluorescent Channel
por: Zhang, Haoqing, et al.
Publicado: (2021)

Grandmother’s Diet Matters: Early Life Programming with Sucrose Influences Metabolic and Lipid Parameters in Second Generation of Rats
por: Školníková, Elena, et al.
Publicado: (2020)

Plasma Cell-Free DNA in Paediatric Lymphomas
por: Mussolin, Lara, et al.
Publicado: (2013)

NETosis provides the link between activation of neutrophils on hemodialysis membrane and comorbidities in dialyzed patients
por: Korabecna, Marie, et al.
Publicado: (2016)

Detection of Apparent Cell-free M. tuberculosis DNA from Plasma
por: Click, E. S., et al.
Publicado: (2018)

Clinical utility of plasma cell-free DNA in gliomas
por: Carpenter, Erica L, et al.
Publicado: (2022)

Pipecolic acid confers systemic immunity by regulating free radicals
por: Wang, Caixia, et al.
Publicado: (2018)

Circulating free plasma tumor DNA in patients with advanced gastric cancer receiving systemic chemotherapy
por: Normando, Sávia Raquel Costa, et al.
Publicado: (2018)

Characterization of Mitochondrial DNA Methylation of Alzheimer’s Disease in Plasma Cell-Free DNA
por: Ding, Binrong, et al.
Publicado: (2023)

Nuclease deficiencies alter plasma cell-free DNA methylation profiles
por: Han, Diana S.C., et al.
Publicado: (2021)

Over‐shedding of donor‐derived cell‐free DNA at immune‐related regions into plasma of lung transplant recipient
por: Luo, Jiaqi, et al.
Publicado: (2022)

Diurnal stability of cell-free DNA and cell-free RNA in human plasma samples
por: Wagner, Josiah T., et al.
Publicado: (2020)

Quantitation of cell-free DNA and RNA in plasma during tumor progression in rats
por: García-Olmo, Dolores C, et al.
Publicado: (2013)

Plasma cell-free DNA in patients needing mechanical ventilation
por: Okkonen, Marjatta, et al.
Publicado: (2011)

Plasma circulating cell-free mitochondrial DNA in depressive disorders
por: Fernström, Johan, et al.
Publicado: (2021)

Plasma cell‐free DNA analysis for COVID‐19 and beyond
por: Ju, Jia, et al.
Publicado: (2022)

Pharmacogenetic interaction between dexamethasone and Cd36-deficient segment of spontaneously hypertensive rat chromosome 4 affects triacylglycerol and cholesterol distribution into lipoprotein fractions
por: Krupková, Michaela, et al.
Publicado: (2010)

Pharmacogenomic analysis of retinoic-acid induced dyslipidemia in congenic rat model
por: Krupková, Michaela, et al.
Publicado: (2014)

Plasma free DNA: Evaluation of temperature-associated storage effects observed for Roche Cell-Free DNA collection tubes
por: Enko, Dietmar, et al.
Publicado: (2019)

Plasma contains ultrashort single-stranded DNA in addition to nucleosomal cell-free DNA
por: Cheng, Jordan, et al.
Publicado: (2022)

DNA methylation analysis explores the molecular basis of plasma cell-free DNA fragmentation
por: An, Yunyun, et al.
Publicado: (2023)

The Most Favourable Procedure for the Isolation of Cell-Free DNA from the Plasma of Iso-Immunized RHD-Negative Pregnant Women
por: Rather, Riyaz Ahmad, et al.
Publicado: (2015)

Free-radical-mediated DNA binding.
por: O'Brien, P J
Publicado: (1985)

Lack of reliability of nanotechnology in the of free plasma DNA in samples of patients with prostate cancer
por: Moreno, Ricardo, et al.
Publicado: (2013)

DNA Methylation is Developmentally Regulated for Genes Essential for Cardiogenesis
por: Chamberlain, Alyssa A., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3tgfcbg9b0v2m2m6nuk1orlvo1