The Relationship of Sphingosine Kinase 1 With Pyroptosis Provides a New Strategy for Tumor Therapy

Sphingosine kinase 1 (SPHK1) is a crucial molecule that catalyzes sphingosine to synthesize sphingosine-1-phosphate (S1P), facilitating cell survival signaling. Pyroptosis is a perplexing inflammatory mode of cell death primarily triggered by caspase-1, evoked by the NLRP3 inflammasome. Sphingosine...

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Detalles Bibliográficos
Autores principales: Wang, Xianwang, Yang, Yue, Cai, Wen-Qi, Lu, Yingying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566665/
https://www.ncbi.nlm.nih.gov/pubmed/33123153
http://dx.doi.org/10.3389/fimmu.2020.574990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566665/
https://www.ncbi.nlm.nih.gov/pubmed/33123153
http://dx.doi.org/10.3389/fimmu.2020.574990

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