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Renal proximal tubular NEMO plays a critical role in ischemic acute kidney injury

We determined that renal proximal tubular (PT) NF-κB essential modulator (NEMO) plays a direct and critical role in ischemic acute kidney injury (AKI) using mice lacking renal PT NEMO and by targeted renal PT NEMO inhibition with mesoscale nanoparticle–encapsulated NEMO binding peptide (NBP MNP). We...

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Detalles Bibliográficos
Autores principales:	Han, Sang Jun, Williams, Ryan M., Kim, Mihwa, Heller, Daniel A., D’Agati, Vivette, Schmidt-Supprian, Marc, Lee, H. Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566738/ https://www.ncbi.nlm.nih.gov/pubmed/32941183 http://dx.doi.org/10.1172/jci.insight.139246

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