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Upper-room ultraviolet air disinfection might help to reduce COVID-19 transmission in buildings: a feasibility study

As the world’s economies come out of the lockdown imposed by the COVID-19 pandemic, there is an urgent need for technologies to mitigate COVID-19 transmission in confined spaces such as buildings. This feasibility study looks at one such technology, upper-room ultraviolet (UV) air disinfection, that...

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Autores principales: Beggs, Clive B., Avital, Eldad J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566754/
https://www.ncbi.nlm.nih.gov/pubmed/33083158
http://dx.doi.org/10.7717/peerj.10196
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author Beggs, Clive B.
Avital, Eldad J.
author_facet Beggs, Clive B.
Avital, Eldad J.
author_sort Beggs, Clive B.
collection PubMed
description As the world’s economies come out of the lockdown imposed by the COVID-19 pandemic, there is an urgent need for technologies to mitigate COVID-19 transmission in confined spaces such as buildings. This feasibility study looks at one such technology, upper-room ultraviolet (UV) air disinfection, that can be safely used while humans are present in the room space, and which has already proven its efficacy as an intervention to inhibit the transmission of airborne diseases such as measles and tuberculosis. Using published data from various sources, it is shown that the SARS-CoV-2 virus, the causative agent of COVID-19, is highly likely to be susceptible to UV-C damage when suspended in air, with a UV susceptibility constant likely to be in the region 0.377–0.590 m(2)/J, similar to that for other aerosolised coronaviruses. As such, the UV-C flux required to disinfect the virus is expected to be acceptable and safe for upper-room applications. Through analysis of expected and worst-case scenarios, the efficacy of the upper-room UV-C approach for reducing COVID-19 transmission in confined spaces (with moderate but sufficient ceiling height) is demonstrated. Furthermore, it is shown that with SARS-CoV-2, it should be possible to achieve high equivalent air change rates using upper-room UV air disinfection, suggesting that the technology might be particularly applicable to poorly ventilated spaces.
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spelling pubmed-75667542020-10-19 Upper-room ultraviolet air disinfection might help to reduce COVID-19 transmission in buildings: a feasibility study Beggs, Clive B. Avital, Eldad J. PeerJ Microbiology As the world’s economies come out of the lockdown imposed by the COVID-19 pandemic, there is an urgent need for technologies to mitigate COVID-19 transmission in confined spaces such as buildings. This feasibility study looks at one such technology, upper-room ultraviolet (UV) air disinfection, that can be safely used while humans are present in the room space, and which has already proven its efficacy as an intervention to inhibit the transmission of airborne diseases such as measles and tuberculosis. Using published data from various sources, it is shown that the SARS-CoV-2 virus, the causative agent of COVID-19, is highly likely to be susceptible to UV-C damage when suspended in air, with a UV susceptibility constant likely to be in the region 0.377–0.590 m(2)/J, similar to that for other aerosolised coronaviruses. As such, the UV-C flux required to disinfect the virus is expected to be acceptable and safe for upper-room applications. Through analysis of expected and worst-case scenarios, the efficacy of the upper-room UV-C approach for reducing COVID-19 transmission in confined spaces (with moderate but sufficient ceiling height) is demonstrated. Furthermore, it is shown that with SARS-CoV-2, it should be possible to achieve high equivalent air change rates using upper-room UV air disinfection, suggesting that the technology might be particularly applicable to poorly ventilated spaces. PeerJ Inc. 2020-10-13 /pmc/articles/PMC7566754/ /pubmed/33083158 http://dx.doi.org/10.7717/peerj.10196 Text en © 2020 Beggs and Avital https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Microbiology
Beggs, Clive B.
Avital, Eldad J.
Upper-room ultraviolet air disinfection might help to reduce COVID-19 transmission in buildings: a feasibility study
title Upper-room ultraviolet air disinfection might help to reduce COVID-19 transmission in buildings: a feasibility study
title_full Upper-room ultraviolet air disinfection might help to reduce COVID-19 transmission in buildings: a feasibility study
title_fullStr Upper-room ultraviolet air disinfection might help to reduce COVID-19 transmission in buildings: a feasibility study
title_full_unstemmed Upper-room ultraviolet air disinfection might help to reduce COVID-19 transmission in buildings: a feasibility study
title_short Upper-room ultraviolet air disinfection might help to reduce COVID-19 transmission in buildings: a feasibility study
title_sort upper-room ultraviolet air disinfection might help to reduce covid-19 transmission in buildings: a feasibility study
topic Microbiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566754/
https://www.ncbi.nlm.nih.gov/pubmed/33083158
http://dx.doi.org/10.7717/peerj.10196
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