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Integrating multiple microarray dataset analysis and machine learning methods to reveal the key genes and regulatory mechanisms underlying human intervertebral disc degeneration

Intervertebral disc degeneration (IDD), a major cause of lower back pain, has multiple contributing factors including genetics, environment, age, and loading history. Bioinformatics analysis has been extensively used to identify diagnostic biomarkers and therapeutic targets for IDD diagnosis and tre...

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Detalles Bibliográficos
Autores principales: Chang, Hongze, Yang, Xiaolong, You, Kemin, Jiang, Mingwei, Cai, Feng, Zhang, Yan, Liu, Liang, Liu, Hui, Liu, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566771/
https://www.ncbi.nlm.nih.gov/pubmed/33083145
http://dx.doi.org/10.7717/peerj.10120