A simplified method to produce mRNAs and functional proteins from synthetic double-stranded DNA templates

We present a method to synthesize mRNAs from synthetic DNA templates that produce biologically active proteins. To illustrate utility, we constructed five unique synthetic DNA templates, produced mRNAs and demonstrated biologic activity of their translated proteins. Examples include secreted lucifer...

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Detalles Bibliográficos
Autores principales: Tossberg, John T, Esmond, Tashawna M, Aune, Thomas M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2020
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566775/
https://www.ncbi.nlm.nih.gov/pubmed/32815735
http://dx.doi.org/10.2144/btn-2020-0037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566775/
https://www.ncbi.nlm.nih.gov/pubmed/32815735
http://dx.doi.org/10.2144/btn-2020-0037

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