Cargando…

Efavirenz induces DNA damage response pathway in lung cancer

The cell-cycle related genes are potential gene targets in understanding the effects of efavirenz (EFV) in lung cancer. The present study aimed at investigating the expression changes of cell-cycle related genes in response to EFV drug treatment in human non-small cell lung carcinoma (A549) and norm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marima, Rahaba, Hull, Rodney, Dlamini, Zodwa, Penny, Clement
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566803/ https://www.ncbi.nlm.nih.gov/pubmed/33110481 http://dx.doi.org/10.18632/oncotarget.27725

Ejemplares similares

Efavirenz and Lopinavir/Ritonavir Alter Cell Cycle Regulation in Lung Cancer
por: Marima, Rahaba, et al.
Publicado: (2020)

The profiling, identification, quantification and analysis of differentially expressed genes (DEGs) in response to drug treatment in lung cancer
por: Marima, Rahaba, et al.
Publicado: (2021)

Artificial intelligence (AI) and big data in cancer and precision oncology
por: Dlamini, Zodwa, et al.
Publicado: (2020)

HIV-Associated Cancer Biomarkers: A Requirement for Early Diagnosis
por: Dlamini, Zodwa, et al.
Publicado: (2021)

Prostate Cancer Disparities and Management in Southern Africa: Insights into Practices, Norms and Values
por: Marima, Rahaba, et al.
Publicado: (2022)

In Silico Bioinformatics Analysis on the Role of Long Non-Coding RNAs as Drivers and Gatekeepers of Androgen-Independent Prostate Cancer Using LNCaP and PC-3 Cells
por: Mbeje, Mandisa, et al.
Publicado: (2023)

Role and Merits of Green Based Nanocarriers in Cancer Treatment
por: Elbagory, Abdulrahman M., et al.
Publicado: (2021)

Competing Endogenous RNA (ceRNA) Networks and Splicing Switches in Cervical Cancer: HPV Oncogenesis, Clinical Significance and Therapeutic Opportunities
por: Basera, Afra, et al.
Publicado: (2022)

Viral Encoded miRNAs in Tumorigenesis: Theranostic Opportunities in Precision Oncology
por: Hull, Rodney, et al.
Publicado: (2022)

Role of Precision Oncology in Type II Endometrial and Prostate Cancers in the African Population: Global Cancer Genomics Disparities
por: Marima, Rahaba, et al.
Publicado: (2022)

The Catastrophic HPV/HIV Dual Viral Oncogenomics in Concert with Dysregulated Alternative Splicing in Cervical Cancer
por: Marima, Rahaba, et al.
Publicado: (2021)

Many Voices in a Choir: Tumor-Induced Neurogenesis and Neuronal Driven Alternative Splicing Sound Like Suspects in Tumor Growth and Dissemination
por: Dlamini, Zodwa, et al.
Publicado: (2021)

MicroRNA and Alternative mRNA Splicing Events in Cancer Drug Response/Resistance: Potent Therapeutic Targets
por: Marima, Rahaba, et al.
Publicado: (2021)

Dissecting Microbiome-Derived SCFAs in Prostate Cancer: Analyzing Gut Microbiota, Racial Disparities, and Epigenetic Mechanisms
por: Miya, Thabiso Victor, et al.
Publicado: (2023)

Esophageal cancer genetics in South Africa
por: Alaouna, Mohammed, et al.
Publicado: (2019)

Exploiting the Molecular Basis of Oesophageal Cancer for Targeted Therapies and Biomarkers for Drug Response: Guiding Clinical Decision-Making
por: Mbatha, Sikhumbuzo, et al.
Publicado: (2022)

The role played by alternative splicing in antigenic variability in human endo-parasites
por: Hull, Rodney, et al.
Publicado: (2014)

Can the HIV-1 splicing machinery be targeted for drug discovery?
por: Dlamini, Zodwa, et al.
Publicado: (2017)

LncRNAs and the Angiogenic Switch in Cancer: Clinical Significance and Therapeutic Opportunities
por: Mabeta, Peace, et al.
Publicado: (2022)

Regulation of alternative splicing in obesity-induced hypertension
por: Dlamini, Zodwa, et al.
Publicado: (2019)

Human Immunodeficiency Virus-1 (HIV-1)-Mediated Apoptosis: New Therapeutic Targets
por: Mbita, Zukile, et al.
Publicado: (2014)

Reports of Plant-Derived Nanoparticles for Prostate Cancer Therapy
por: Elbagory, Abdulrahman M., et al.
Publicado: (2023)

Overcoming the Challenges of Phytochemicals in Triple Negative Breast Cancer Therapy: The Path Forward
por: Alaouna, Mohammed, et al.
Publicado: (2023)

Translocator Protein (TSPO) as a Potential Biomarker in Human Cancers
por: Bhoola, Nimisha H., et al.
Publicado: (2018)

Colorectal Cancer Genetics, Incidence and Risk Factors: In Search for Targeted Therapies
por: Hull, Rodney, et al.
Publicado: (2020)

Abnormalities in Alternative Splicing of Apoptotic Genes and Cardiovascular Diseases
por: Dlamini, Zodwa, et al.
Publicado: (2015)

Abnormalities in alternative splicing of angiogenesis-related genes and their role in HIV-related cancers
por: Mthembu, Nonkululeko N, et al.
Publicado: (2017)

Immunosuppressive Signaling Pathways as Targeted Cancer Therapies
por: Setlai, Botle Precious, et al.
Publicado: (2022)

The Role of MicroRNAs in Kidney Disease
por: Mukhadi, Sydwell, et al.
Publicado: (2015)

RBBP6 Is Abundantly Expressed in Human Cervical Carcinoma and May Be Implicated in Its Malignant Progression
por: Dlamini, Zodwa, et al.
Publicado: (2019)

Genetic Drivers of Head and Neck Squamous Cell Carcinoma: Aberrant Splicing Events, Mutational Burden, HPV Infection and Future Targets
por: Dlamini, Zodwa, et al.
Publicado: (2021)

Genomic Interplay between Neoneurogenesis and Neoangiogenesis in Carcinogenesis: Therapeutic Interventions
por: Dlamini, Zodwa, et al.
Publicado: (2023)

Prognostic Alternative Splicing Signatures in Esophageal Carcinoma
por: Dlamini, Zodwa, et al.
Publicado: (2021)

Etoposide-induced DNA damage affects multiple cellular pathways in addition to DNA damage response
por: Wei, Fengxiang, et al.
Publicado: (2018)

Alternative Splicing Events and Their Clinical Significance in Colorectal Cancer: Targeted Therapeutic Opportunities
por: Manabile, Mosebo Armstrong, et al.
Publicado: (2023)

Editorial: Cholesterol and cancer drug resistance: Molecular, signaling, and therapeutic aspects
por: Kaur, Mandeep, et al.
Publicado: (2022)

MicroRNA Interrelated Epithelial Mesenchymal Transition (EMT) in Glioblastoma
por: Setlai, Botle Precious, et al.
Publicado: (2022)

Deubiquitylating Enzymes and DNA Damage Response Pathways
por: Jacq, Xavier, et al.
Publicado: (2013)

Cervical cancer in low and middle-income countries
por: Hull, Rodney, et al.
Publicado: (2020)

Microbiomes, Epigenomics, Immune Response, and Splicing Signatures Interplay: Potential Use of Combination of Regulatory Pathways as Targets for Malignant Mesothelioma
por: Setlai, Botle Precious, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jr8u0hskmtd09qh236jdk7k1d0