Cellular senescence contributes to radiation-induced hyposalivation by affecting the stem/progenitor cell niche

Radiotherapy for head and neck cancer is associated with impairment of salivary gland function and consequent xerostomia, which has a devastating effect on the quality of life of the patients. The mechanism of radiation-induced salivary gland damage is not completely understood. Cellular senescence...

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Detalles Bibliográficos
Autores principales: Peng, Xiaohong, Wu, Yi, Brouwer, Uilke, van Vliet, Thijmen, Wang, Boshi, Demaria, Marco, Barazzuol, Lara, Coppes, Rob P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566836/
https://www.ncbi.nlm.nih.gov/pubmed/33056980
http://dx.doi.org/10.1038/s41419-020-03074-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566836/
https://www.ncbi.nlm.nih.gov/pubmed/33056980
http://dx.doi.org/10.1038/s41419-020-03074-9

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