Recombinant thrombomodulin alleviates oxidative stress without compromising host resistance to infection in rats infected with methicillin-resistant Staphylococcus aureus

Recombinant thrombomodulin (rTM) has been used for treatment of sepsis-associated disseminated intravascular coagulation. Recent studies have suggested that anticoagulant therapy might dampen the protective role of immunothrombosis. We examined if rTM might worsen infectious diseases. Male Sprague–D...

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Detalles Bibliográficos
Autores principales: Ito, Takashi, Shrestha, Binita, Kakihana, Yasuyuki, Maruyama, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566838/
https://www.ncbi.nlm.nih.gov/pubmed/33060764
http://dx.doi.org/10.1038/s41598-020-74529-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7566838/
https://www.ncbi.nlm.nih.gov/pubmed/33060764
http://dx.doi.org/10.1038/s41598-020-74529-4

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