HOPS/Tmub1 involvement in the NF-kB-mediated inflammatory response through the modulation of TRAF6

HOPS/Tmub1 is a ubiquitously expressed transmembrane ubiquitin-like protein that shuttles between nucleus and cytoplasm during cell cycle progression. HOPS causes cell cycle arrest in G(0)/G(1) phase, an event associated to stabilization of p19(Arf), an important tumor suppressor protein. Moreover,...

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Detalles Bibliográficos
Autores principales: Bellet, Marina Maria, Pieroni, Stefania, Castelli, Marilena, Piobbico, Danilo, Fallarino, Francesca, Romani, Luigina, Della-Fazia, Maria Agnese, Servillo, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567074/
https://www.ncbi.nlm.nih.gov/pubmed/33060567
http://dx.doi.org/10.1038/s41419-020-03086-5

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