Network integration and modelling of dynamic drug responses at multi-omics levels

Uncovering cellular responses from heterogeneous genomic data is crucial for molecular medicine in particular for drug safety. This can be realized by integrating the molecular activities in networks of interacting proteins. As proof-of-concept we challenge network modeling with time-resolved proteo...

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Detalles Bibliográficos
Autores principales: Selevsek, Nathalie, Caiment, Florian, Nudischer, Ramona, Gmuender, Hans, Agarkova, Irina, Atkinson, Francis L., Bachmann, Ivo, Baier, Vanessa, Barel, Gal, Bauer, Chris, Boerno, Stefan, Bosc, Nicolas, Clayton, Olivia, Cordes, Henrik, Deeb, Sally, Gotta, Stefano, Guye, Patrick, Hersey, Anne, Hunter, Fiona M. I., Kunz, Laura, Lewalle, Alex, Lienhard, Matthias, Merken, Jort, Minguet, Jasmine, Oliveira, Bernardo, Pluess, Carla, Sarkans, Ugis, Schrooders, Yannick, Schuchhardt, Johannes, Smit, Ines, Thiel, Christoph, Timmermann, Bernd, Verheijen, Marcha, Wittenberger, Timo, Wolski, Witold, Zerck, Alexandra, Heymans, Stephane, Kuepfer, Lars, Roth, Adrian, Schlapbach, Ralph, Niederer, Steven, Herwig, Ralf, Kleinjans, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567116/
https://www.ncbi.nlm.nih.gov/pubmed/33060801
http://dx.doi.org/10.1038/s42003-020-01302-8

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