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Metabolic profiling shows pre‐existing mitochondrial dysfunction contributes to muscle loss in a model of ICU‐acquired weakness

BACKGROUND: Surgery can lead to significant muscle loss, which increases recovery time and associates with increased mortality. Muscle loss is not uniform, with some patients losing significant muscle mass and others losing relatively little, and is likely to be accompanied by marked changes in circ...

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Detalles Bibliográficos
Autores principales: Kemp, Paul R., Paul, Richard, Hinken, Aaron C., Neil, David, Russell, Alan, Griffiths, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567140/
https://www.ncbi.nlm.nih.gov/pubmed/32677363
http://dx.doi.org/10.1002/jcsm.12597