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Genome-scale metabolic models highlight stage-specific differences in essential metabolic pathways in Trypanosoma cruzi

Chagas disease is a neglected tropical disease and a leading cause of heart failure in Latin America caused by a protozoan called Trypanosoma cruzi. This parasite presents a complex multi-stage life cycle. Anti-Chagas drugs currently available are limited to benznidazole and nifurtimox, both with se...

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Detalles Bibliográficos
Autores principales:	Shiratsubaki, Isabel S., Fang, Xin, Souza, Rodolpho O. O., Palsson, Bernhard O., Silber, Ariel M., Siqueira-Neto, Jair L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567352/ https://www.ncbi.nlm.nih.gov/pubmed/33021977 http://dx.doi.org/10.1371/journal.pntd.0008728

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