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Synergistic apoptotic effects in cancer cells by the combination of CLK and Bcl-2 family inhibitors

Emerging evidence indicates that alternative splicing plays a critical role in cancer progression through abnormal expression or mutation of splicing factors. Small-molecule splicing modulators have recently attracted considerable attention as a novel class of cancer therapeutics. CDC-like kinases (...

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Detalles Bibliográficos
Autores principales:	Murai, Aiko, Ebara, Shunsuke, Sasaki, Satoshi, Ohashi, Tomohiro, Miyazaki, Tohru, Nomura, Toshiyuki, Araki, Shinsuke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567398/ https://www.ncbi.nlm.nih.gov/pubmed/33064779 http://dx.doi.org/10.1371/journal.pone.0240718

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