Cargando…

Functional Analysis of the 3ʹ Untranslated Region of the Human GRIN1 Gene in Regulating Gene Expression in vitro

PURPOSE: Abnormal expression of the NR1 subunit of the N-methyl-d-aspartate (NMDA) receptor may potentially increase the susceptibility to neuropsychiatric diseases. The purpose of this study was to investigate the functional sequence of the 3ʹUTR of the human GRIN1 gene, which encodes the GluN1 rec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Yong-ping, Wu, Xue, Meng, Jing-hua, Yao, Jun, Wang, Bao-jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567549/ https://www.ncbi.nlm.nih.gov/pubmed/33116535 http://dx.doi.org/10.2147/NDT.S268753

Ejemplares similares

The 3ʹ-untranslated region contributes to the pregnane X receptor (PXR) expression down-regulation by PXR ligands and up-regulation by glucocorticoids
por: Smutny, Tomas, et al.
Publicado: (2020)

RBM24 inhibits the translation of SARS-CoV-2 polyproteins by targeting the 5ʹ-untranslated region
por: Yao, Yongxuan, et al.
Publicado: (2023)

Phylogenetic analysis of the 5ʹ untranslated region of HCV from cirrhotic patients in Khyber Pakhtunkhwa, Pakistan
por: Ullah, Amin, et al.
Publicado: (2021)

A variant in the 3ʹ-untranslated region of the MC2R gene decreases the risk of schizophrenia in a female Han Chinese population
por: Tang, Liang, et al.
Publicado: (2021)

Association between polymorphisms in the GRIN1 gene 5′ regulatory region and schizophrenia in a northern Han Chinese population and haplotype effects on protein expression in vitro
por: Liu, Yong-ping, et al.
Publicado: (2019)

Assessment of NMDA receptor genes (GRIN2A, GRIN2B and GRIN2C) as candidate genes in the development of degenerative lumbar scoliosis
por: KIM, KI-TACK, et al.
Publicado: (2013)

AU-Rich Long 3′ Untranslated Region Regulates Gene Expression in Bacteria
por: Zhao, Ju-Ping, et al.
Publicado: (2018)

Regulation of eukaryotic gene expression by the untranslated gene regions and other non-coding elements
por: Barrett, Lucy W., et al.
Publicado: (2012)

Posttranscriptional Gene Regulation by Spatial Rearrangement of the 3′ Untranslated Region
por: Eberle, Andrea B, et al.
Publicado: (2008)

Alternative Polyadenylation of mRNAs: 3′-Untranslated Region Matters in Gene Expression
por: Yeh, Hsin-Sung, et al.
Publicado: (2016)

Characterization of 3'-untranslated region of the mouse GDNF gene
por: Oh-hashi, Kentaro, et al.
Publicado: (2012)

F11. TRANSLATIONAL STUDY OF GRIN1, GRIN2A AND 2B GENE EXPRESSION IN PATIENTS WITH SCHIZOPHRENIA AND ANIMAL MODELS
por: Marcelino, Loureiro Camila, et al.
Publicado: (2018)

Key role of the 3' untranslated region in the cell cycle regulated expression of the Leishmania infantum histone H2A genes: minor synergistic effect of the 5' untranslated region
por: Abanades, Daniel R, et al.
Publicado: (2009)

Aldosterone regulates a 5ʹ variant sgk1 transcript via a shared hormone response element in the sgk1 5ʹ regulatory region
por: Raikwar, Nandita S., et al.
Publicado: (2017)

The role of RNA structure at 5′ untranslated region in microRNA-mediated gene regulation
por: Gu, Wanjun, et al.
Publicado: (2014)

Genetic variant in 3’ untranslated region of the mouse pycard gene regulates inflammasome activity
por: Ritchey, Brian, et al.
Publicado: (2021)

The Role of the 3' Untranslated Region in the Post-Transcriptional Regulation of KLF6 Gene Expression in Hepatocellular Carcinoma
por: Diab, Thoria, et al.
Publicado: (2013)

Argonaute binding within 3′-untranslated regions poorly predicts gene repression
por: Chu, Yongjun, et al.
Publicado: (2020)

Multiple microRNAs regulate human FOXP2 gene expression by targeting sequences in its 3′ untranslated region
por: Fu, Lijuan, et al.
Publicado: (2014)

Distinct roles of GRIN2A and GRIN2B variants in neurological conditions
por: Myers, Scott J, et al.
Publicado: (2019)

A piggyBac-based reporter system for scalable in vitro and in vivo analysis of 3′ untranslated region-mediated gene regulation
por: Chaudhury, Arindam, et al.
Publicado: (2014)

Characterization and functional analyses of the human HTR1A gene: 5’ regulatory region modulates gene expression in vitro
por: Wu, Xue, et al.
Publicado: (2018)

Strength and ductility with {101̄1} — {101̄2} double twinning in a magnesium alloy
por: Lentz, M., et al.
Publicado: (2016)

Both prokaryotes and eukaryotes produce an immune response against plasmids with 5ʹ-GTTTGTT-3ʹ
por: Li, Nan, et al.
Publicado: (2022)

Anuario 9́3 : estudios sociales.
Publicado: (1994)

Rela©ʹ{tilde}oes internacionais
por: Gon©ʹalves, Williams da Silva
Publicado: (2002)

Untranslated regions of mRNAs
por: Mignone, Flavio, et al.
Publicado: (2002)

Glutamate Receptor Gene GRIN2A, Coffee, and Parkinson Disease
por: Hamza, Taye H., et al.
Publicado: (2014)

Increased nucleotide polymorphic changes in the 5′-untranslated region of δ-catenin (CTNND2) gene in prostate cancer
por: Wang, Tao, et al.
Publicado: (2008)

PM339A. The GRIN2B and GRIN2A genes are associated with continuous performance test variables in attention-deficit/hyperactivity disorder
por: Kim, Soo Yeon, et al.
Publicado: (2016)

Transcription Factor CEBPB Inhibits the Expression of the Human HTR1A by Binding to 5′ Regulatory Region In Vitro
por: Liu, Yong-Ping, et al.
Publicado: (2019)

Porcine SOX9 Gene Expression Is Influenced by an 18bp Indel in the 5’-Untranslated Region
por: Brenig, Bertram, et al.
Publicado: (2015)

The ODC 3′-Untranslated Region and 5′-Untranslated Region Contain cis-Regulatory Elements: Implications for Carcinogenesis
por: Nowotarski, Shannon L., et al.
Publicado: (2017)

Rett and Rett‐like syndrome: Expanding the genetic spectrum to KIF1A and GRIN1 gene
por: Wang, Jiaping, et al.
Publicado: (2019)

Estratifica©ʹ{tilde}ao social no Brasil : suas origens historicas e suas rela©ʹ{tilde}oes com a organiza©ʹ{tilde}ao politica do pa©Ưs.
por: Torres, João Camilo de Oliveira. 1915-1973
Publicado: (1965)

Study of Early Onset Schizophrenia: Associations of GRIN2A and GRIN2B Polymorphisms
por: Poltavskaya, Evgeniya G., et al.
Publicado: (2021)

O que ©♭ educa©ʹ{tilde}ao
por: Brandão, Carlos Rodrigues
Publicado: (1981)

Properties of untranslated regions of the S. cerevisiae genome
por: Tuller, Tamir, et al.
Publicado: (2009)

The 5′-Untranslated Region of Picornaviral Genomes
por: Agol, Vadim I.
Publicado: (1991)

Functional Characterization of a Single Nucleotide Polymorphism in the 3' Untranslated Region of Sheep DLX3 Gene
por: Rong, Enguang, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_63a85vku0ia27f45d9rjnd8f7m