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Modulating lung immune cells by pulmonary delivery of antigen-specific nanoparticles to treat autoimmune disease

Antigen-specific particles can treat autoimmunity, and pulmonary delivery may provide for easier delivery than intravenous or subcutaneous routes. The lung is a “hub” for autoimmunity where autoreactive T cells pass before arriving at disease sites. Here, we report that targeting lung antigen-presen...

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Detalles Bibliográficos
Autores principales: Saito, Eiji, Gurczynski, Stephen J., Kramer, Kevin R., Wilke, Carol A., Miller, Stephen D., Moore, Bethany B., Shea, Lonnie D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567592/
https://www.ncbi.nlm.nih.gov/pubmed/33067238
http://dx.doi.org/10.1126/sciadv.abc9317