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Unbiased homeologous recombination during pneumococcal transformation allows for multiple chromosomal integration events

The spread of antimicrobial resistance and vaccine escape in the human pathogen Streptococcus pneumoniae can be largely attributed to competence-induced transformation. Here, we studied this process at the single-cell level. We show that within isogenic populations, all cells become naturally compet...

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Detalles Bibliográficos
Autores principales:	Kurushima, Jun, Campo, Nathalie, van Raaphorst, Renske, Cerckel, Guillaume, Polard, Patrice, Veening, Jan-Willem
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Microbiology and Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567608/ https://www.ncbi.nlm.nih.gov/pubmed/32965219 http://dx.doi.org/10.7554/eLife.58771

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