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Adipocyte-specific deletion of Tcf7l2 induces dysregulated lipid metabolism and impairs glucose tolerance in mice

AIMS/HYPOTHESIS: Transcription factor 7-like 2 (TCF7L2) is a downstream effector of the Wnt/β-catenin signalling pathway implicated in type 2 diabetes risk through genome-wide association studies. Although its expression is critical for adipocyte development, the potential roles of changes in adipos...

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Detalles Bibliográficos
Autores principales:	Nguyen-Tu, Marie-Sophie, Martinez-Sanchez, Aida, Leclerc, Isabelle, Rutter, Guy A., da Silva Xavier, Gabriela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567653/ https://www.ncbi.nlm.nih.gov/pubmed/33068125 http://dx.doi.org/10.1007/s00125-020-05292-4

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