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Higher binding affinity of furin for SARS-CoV-2 spike (S) protein D614G mutant could be associated with higher SARS-CoV-2 infectivity

OBJECTIVE: The coronavirus disease 2019 (COVID-19) pandemic has caused an exponential rise in death rates and hospitalizations. The aim of this study was to characterize the D614G substitution in the severe acute respiratory syndome coronavirus 2 (SARS-CoV-2) spike glycoprotein (S protein), which ma...

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Detalles Bibliográficos
Autores principales:	Mohammad, Anwar, Alshawaf, Eman, Marafie, Sulaiman K., Abu-Farha, Mohamed, Abubaker, Jehad, Al-Mulla, Fahd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567667/ https://www.ncbi.nlm.nih.gov/pubmed/33075532 http://dx.doi.org/10.1016/j.ijid.2020.10.033

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