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Guanfacine’s mechanism of action in treating prefrontal cortical disorders: Successful translation across species
The selective norepinephrine (NE) α2A-adrenoceptor (α2A-AR) agonist, guanfacine (Intuniv™), is FDA-approved for treating Attention Deficit Hyperactivity Disorder (ADHD) based on research in animals, a translational success story. Guanfacine is also widely used off-label in additional mental disorder...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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The Author(s). Published by Elsevier Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567669/ https://www.ncbi.nlm.nih.gov/pubmed/33075480 http://dx.doi.org/10.1016/j.nlm.2020.107327 |