Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants

The genetic and clinical characteristics of breast tumors with germline variants, including their association with biallelic inactivation through loss-of-heterozygosity (LOH) and second somatic mutations, remain elusive. We analyzed germline variants of 11 breast cancer susceptibility genes for 1,99...

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Detalles Bibliográficos
Autores principales: Inagaki-Kawata, Yukiko, Yoshida, Kenichi, Kawaguchi-Sakita, Nobuko, Kawashima, Masahiro, Nishimura, Tomomi, Senda, Noriko, Shiozawa, Yusuke, Takeuchi, Yasuhide, Inoue, Yoshikage, Sato-Otsubo, Aiko, Fujii, Yoichi, Nannya, Yasuhito, Suzuki, Eiji, Takada, Masahiro, Tanaka, Hiroko, Shiraishi, Yuichi, Chiba, Kenichi, Kataoka, Yuki, Torii, Masae, Yoshibayashi, Hiroshi, Yamagami, Kazuhiko, Okamura, Ryuji, Moriguchi, Yoshio, Kato, Hironori, Tsuyuki, Shigeru, Yamauchi, Akira, Suwa, Hirofumi, Inamoto, Takashi, Miyano, Satoru, Ogawa, Seishi, Toi, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567851/
https://www.ncbi.nlm.nih.gov/pubmed/33067557
http://dx.doi.org/10.1038/s42003-020-01301-9

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