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Structure of inhibitor-bound mammalian complex I

Respiratory complex I (NADH:ubiquinone oxidoreductase) captures the free energy from oxidising NADH and reducing ubiquinone to drive protons across the mitochondrial inner membrane and power oxidative phosphorylation. Recent cryo-EM analyses have produced near-complete models of the mammalian comple...

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Detalles Bibliográficos
Autores principales: Bridges, Hannah R., Fedor, Justin G., Blaza, James N., Di Luca, Andrea, Jussupow, Alexander, Jarman, Owen D., Wright, John J., Agip, Ahmed-Noor A., Gamiz-Hernandez, Ana P., Roessler, Maxie M., Kaila, Ville R. I., Hirst, Judy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567858/
https://www.ncbi.nlm.nih.gov/pubmed/33067417
http://dx.doi.org/10.1038/s41467-020-18950-3