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Structure of inhibitor-bound mammalian complex I
Respiratory complex I (NADH:ubiquinone oxidoreductase) captures the free energy from oxidising NADH and reducing ubiquinone to drive protons across the mitochondrial inner membrane and power oxidative phosphorylation. Recent cryo-EM analyses have produced near-complete models of the mammalian comple...
Autores principales: | Bridges, Hannah R., Fedor, Justin G., Blaza, James N., Di Luca, Andrea, Jussupow, Alexander, Jarman, Owen D., Wright, John J., Agip, Ahmed-Noor A., Gamiz-Hernandez, Ana P., Roessler, Maxie M., Kaila, Ville R. I., Hirst, Judy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567858/ https://www.ncbi.nlm.nih.gov/pubmed/33067417 http://dx.doi.org/10.1038/s41467-020-18950-3 |
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