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PGC-1β-expressing POMC neurons mediate the effect of leptin on thermoregulation in the mouse
The arcuate nucleus (ARC) of the hypothalamus is a key regulator of food intake, brown adipose tissue (BAT) thermogenesis, and locomotor activity. Whole-body deficiency of the transcriptional coactivator peroxisome proliferator-activated receptor γ (PPARγ) coactivator-1β (PGC-1β) disrupts mouse circ...
Autores principales: | Delezie, Julien, Gill, Jonathan F., Santos, Gesa, Karrer-Cardel, Bettina, Handschin, Christoph |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567876/ https://www.ncbi.nlm.nih.gov/pubmed/33060645 http://dx.doi.org/10.1038/s41598-020-73794-7 |
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