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Activation of SIRT1/PGC 1α/SIRT3 pathway by melatonin provides protection against mitochondrial dysfunction in isoproterenol induced myocardial injury

AIMS: Preventing mitochondrial dysfunction and enhancing mitochondrial health and biogenesis is a crucial therapeutic approach to ameliorate injury following acute myocardial infarction. Although the antioxidant role of melatonin against ischemia/reperfusion injury has been reported, the exact mecha...

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Detalles Bibliográficos
Autores principales:	Naaz, Shamreen, Mishra, Sanatan, Pal, Palash K., Chattopadhyay, Aindrila, Das, Asish R., Bandyopadhyay, Debasish
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567935/ https://www.ncbi.nlm.nih.gov/pubmed/33088945 http://dx.doi.org/10.1016/j.heliyon.2020.e05159

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