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Limb-salvage surgery offers better five-year survival rate than amputation in patients with limb osteosarcoma treated with neoadjuvant chemotherapy. A systematic review and meta-analysis
BACKGROUND: Osteosarcoma is the most common primary bone sarcoma. Currently, the main treatment option for high-grade osteosarcomas is neoadjuvant chemotherapy, followed by surgical resection of the lesion and adjuvant chemotherapy. Limb salvage surgery (LSS) and amputation are the main surgical tec...
Autores principales: | Papakonstantinou, Evgenia, Stamatopoulos, Alexandros, I Athanasiadis, Dimitrios, Kenanidis, Efstathios, Potoupnis, Michael, Haidich, Anna-Bettina, Tsiridis, Eleftherios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7567946/ https://www.ncbi.nlm.nih.gov/pubmed/33088699 http://dx.doi.org/10.1016/j.jbo.2020.100319 |
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