A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2

The recent emergence and rapid global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pose an unprecedented medical and socioeconomic crisis, and the disease caused by it, Coronavirus disease 2019 (COVID-19), was declared a pandemic by the World Health Organization (WHO) o...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Shichuan, Trilling, Mirko, Sutter, Kathrin, Dittmer, Ulf, Lu, Mengji, Zheng, Xin, Yang, Dongliang, Liu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568009/
https://www.ncbi.nlm.nih.gov/pubmed/33068260
http://dx.doi.org/10.1007/s12250-020-00298-z
Descripción
Sumario:The recent emergence and rapid global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pose an unprecedented medical and socioeconomic crisis, and the disease caused by it, Coronavirus disease 2019 (COVID-19), was declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Chinese scientists and physicians rapidly identified the causative pathogen, which turned out to be a novel betacoronavirus with high sequence similarities to bat and pangolin coronaviruses. The scientific community has ignited tremendous efforts to unravel the biological underpinning of SARS-CoV-2, which constitutes the foundation for therapy and vaccine development strategies. Here, we summarize the current state of knowledge on the genome, structure, receptor, and origin of SARS-CoV-2.

Ejemplares similares