A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2

The recent emergence and rapid global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pose an unprecedented medical and socioeconomic crisis, and the disease caused by it, Coronavirus disease 2019 (COVID-19), was declared a pandemic by the World Health Organization (WHO) o...

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Autores principales: Wang, Shichuan, Trilling, Mirko, Sutter, Kathrin, Dittmer, Ulf, Lu, Mengji, Zheng, Xin, Yang, Dongliang, Liu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568009/
https://www.ncbi.nlm.nih.gov/pubmed/33068260
http://dx.doi.org/10.1007/s12250-020-00298-z
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author Wang, Shichuan
Trilling, Mirko
Sutter, Kathrin
Dittmer, Ulf
Lu, Mengji
Zheng, Xin
Yang, Dongliang
Liu, Jia
author_facet Wang, Shichuan
Trilling, Mirko
Sutter, Kathrin
Dittmer, Ulf
Lu, Mengji
Zheng, Xin
Yang, Dongliang
Liu, Jia
author_sort Wang, Shichuan
collection PubMed
description The recent emergence and rapid global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pose an unprecedented medical and socioeconomic crisis, and the disease caused by it, Coronavirus disease 2019 (COVID-19), was declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Chinese scientists and physicians rapidly identified the causative pathogen, which turned out to be a novel betacoronavirus with high sequence similarities to bat and pangolin coronaviruses. The scientific community has ignited tremendous efforts to unravel the biological underpinning of SARS-CoV-2, which constitutes the foundation for therapy and vaccine development strategies. Here, we summarize the current state of knowledge on the genome, structure, receptor, and origin of SARS-CoV-2.
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spelling pubmed-75680092020-10-19 A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2 Wang, Shichuan Trilling, Mirko Sutter, Kathrin Dittmer, Ulf Lu, Mengji Zheng, Xin Yang, Dongliang Liu, Jia Virol Sin Review The recent emergence and rapid global spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pose an unprecedented medical and socioeconomic crisis, and the disease caused by it, Coronavirus disease 2019 (COVID-19), was declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Chinese scientists and physicians rapidly identified the causative pathogen, which turned out to be a novel betacoronavirus with high sequence similarities to bat and pangolin coronaviruses. The scientific community has ignited tremendous efforts to unravel the biological underpinning of SARS-CoV-2, which constitutes the foundation for therapy and vaccine development strategies. Here, we summarize the current state of knowledge on the genome, structure, receptor, and origin of SARS-CoV-2. Springer Singapore 2020-10-17 /pmc/articles/PMC7568009/ /pubmed/33068260 http://dx.doi.org/10.1007/s12250-020-00298-z Text en © Wuhan Institute of Virology, CAS 2020
spellingShingle Review
Wang, Shichuan
Trilling, Mirko
Sutter, Kathrin
Dittmer, Ulf
Lu, Mengji
Zheng, Xin
Yang, Dongliang
Liu, Jia
A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2
title A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2
title_full A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2
title_fullStr A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2
title_full_unstemmed A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2
title_short A Crowned Killer’s Résumé: Genome, Structure, Receptors, and Origin of SARS-CoV-2
title_sort crowned killer’s résumé: genome, structure, receptors, and origin of sars-cov-2
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568009/
https://www.ncbi.nlm.nih.gov/pubmed/33068260
http://dx.doi.org/10.1007/s12250-020-00298-z
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