Cargando…

Rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: A rare entity

BACKGROUND: A diffuse neurofibroma, a variant of neurofibroma, most commonly occurs in young adults and involves the head and neck. In the absence of neurofibromatosis, associated calvarial defect with these swellings is rarely seen. CASE DESCRIPTION: An 18-year-old woman presented with a history of...

Descripción completa

Detalles Bibliográficos
Autores principales: Nehete, Lokesh Suresh, Sharma, Raghavendra, Singh, Prashant Raj, Gupta, Surendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568129/
https://www.ncbi.nlm.nih.gov/pubmed/33093990
http://dx.doi.org/10.25259/SNI_213_2020
_version_ 1783596465590894592
author Nehete, Lokesh Suresh
Sharma, Raghavendra
Singh, Prashant Raj
Gupta, Surendra
author_facet Nehete, Lokesh Suresh
Sharma, Raghavendra
Singh, Prashant Raj
Gupta, Surendra
author_sort Nehete, Lokesh Suresh
collection PubMed
description BACKGROUND: A diffuse neurofibroma, a variant of neurofibroma, most commonly occurs in young adults and involves the head and neck. In the absence of neurofibromatosis, associated calvarial defect with these swellings is rarely seen. CASE DESCRIPTION: An 18-year-old woman presented with a history of rapidly progressive painless large swelling over the bilateral parieto-occipital region of scalp. It was soft and boggy with brownish discoloration of overlying skin. Imaging study showed brilliantly enhancing diffuse lesion involving the bilateral parieto-occipital region of scalp and extending into the extradural region. She underwent excision of lesion. Postoperatively, she developed flap necrosis and it was allowed to heal with the secondary intention. The biopsy findings were consistent with neurofibroma. The patient is on regular follow-up, without any evidence of recurrence at 1 year. CONCLUSION: Rapidly growing solitary diffuse neurofibroma is rare in children and adolescents. Preoperative diagnosis may be difficult and surgical treatment needs to be individualized. These patients need regular follow-up for early detection of recurrence.
format Online
Article
Text
id pubmed-7568129
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Scientific Scholar
record_format MEDLINE/PubMed
spelling pubmed-75681292020-10-21 Rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: A rare entity Nehete, Lokesh Suresh Sharma, Raghavendra Singh, Prashant Raj Gupta, Surendra Surg Neurol Int Case Report BACKGROUND: A diffuse neurofibroma, a variant of neurofibroma, most commonly occurs in young adults and involves the head and neck. In the absence of neurofibromatosis, associated calvarial defect with these swellings is rarely seen. CASE DESCRIPTION: An 18-year-old woman presented with a history of rapidly progressive painless large swelling over the bilateral parieto-occipital region of scalp. It was soft and boggy with brownish discoloration of overlying skin. Imaging study showed brilliantly enhancing diffuse lesion involving the bilateral parieto-occipital region of scalp and extending into the extradural region. She underwent excision of lesion. Postoperatively, she developed flap necrosis and it was allowed to heal with the secondary intention. The biopsy findings were consistent with neurofibroma. The patient is on regular follow-up, without any evidence of recurrence at 1 year. CONCLUSION: Rapidly growing solitary diffuse neurofibroma is rare in children and adolescents. Preoperative diagnosis may be difficult and surgical treatment needs to be individualized. These patients need regular follow-up for early detection of recurrence. Scientific Scholar 2020-10-02 /pmc/articles/PMC7568129/ /pubmed/33093990 http://dx.doi.org/10.25259/SNI_213_2020 Text en Copyright: © 2020 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Nehete, Lokesh Suresh
Sharma, Raghavendra
Singh, Prashant Raj
Gupta, Surendra
Rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: A rare entity
title Rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: A rare entity
title_full Rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: A rare entity
title_fullStr Rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: A rare entity
title_full_unstemmed Rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: A rare entity
title_short Rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: A rare entity
title_sort rapidly growing diffuse neurofibroma of the scalp with calvarial defect in a young woman: a rare entity
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568129/
https://www.ncbi.nlm.nih.gov/pubmed/33093990
http://dx.doi.org/10.25259/SNI_213_2020
work_keys_str_mv AT nehetelokeshsuresh rapidlygrowingdiffuseneurofibromaofthescalpwithcalvarialdefectinayoungwomanarareentity
AT sharmaraghavendra rapidlygrowingdiffuseneurofibromaofthescalpwithcalvarialdefectinayoungwomanarareentity
AT singhprashantraj rapidlygrowingdiffuseneurofibromaofthescalpwithcalvarialdefectinayoungwomanarareentity
AT guptasurendra rapidlygrowingdiffuseneurofibromaofthescalpwithcalvarialdefectinayoungwomanarareentity