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Ultrasensitive CRISPR-based diagnostic for field-applicable detection of Plasmodium species in symptomatic and asymptomatic malaria

Asymptomatic carriers of Plasmodium parasites hamper malaria control and eradication. Achieving malaria eradication requires ultrasensitive diagnostics for low parasite density infections (<100 parasites per microliter blood) that work in resource-limited settings (RLS). Sensitive point-of-care d...

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Detalles Bibliográficos
Autores principales: Lee, Rose A., Puig, Helena De, Nguyen, Peter Q., Angenent-Mari, Nicolaas M., Donghia, Nina M., McGee, James P., Dvorin, Jeffrey D., Klapperich, Catherine M., Pollock, Nira R., Collins, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568265/
https://www.ncbi.nlm.nih.gov/pubmed/32958655
http://dx.doi.org/10.1073/pnas.2010196117