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The design and construction of reference pangenome graphs with minigraph

The recent advances in sequencing technologies enable the assembly of individual genomes to the quality of the reference genome. How to integrate multiple genomes from the same species and make the integrated representation accessible to biologists remains an open challenge. Here, we propose a graph...

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Detalles Bibliográficos
Autores principales: Li, Heng, Feng, Xiaowen, Chu, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568353/
https://www.ncbi.nlm.nih.gov/pubmed/33066802
http://dx.doi.org/10.1186/s13059-020-02168-z