Cargando…

Dexmedetomidine Attenuates Cellular Injury and Apoptosis in H9c2 Cardiomyocytes by Regulating p-38MAPK and Endoplasmic Reticulum Stress

BACKGROUND: Myocardial ischaemia-reperfusion injury (IRI) has been confirmed to induce endoplasmic reticulum stress (ERS) when myocardial cell function continues to deteriorate to a certain degree. The clinical applications of effective tested strategies are sometimes inconsistent with the applicati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Zhipeng, Ling, Xiaoyan, Zhou, Hongmei, Zhang, Caijun, Yan, Weiwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568428/ https://www.ncbi.nlm.nih.gov/pubmed/33116411 http://dx.doi.org/10.2147/DDDT.S265970

Ejemplares similares

Dexmedetomidine at a dose of 1 µM attenuates H9c2 cardiomyocyte injury under 3 h of hypoxia exposure and 3 h of reoxygenation through the inhibition of endoplasmic reticulum stress
por: Zhu, Zhipeng, et al.
Publicado: (2021)

Panax quinquefolium saponin attenuates cardiomyocyte apoptosis induced by thapsigargin through inhibition of endoplasmic reticulum stress
por: Liu, Mi, et al.
Publicado: (2015)

Dexmedetomidine Attenuates Ischemia/Reperfusion-Induced Myocardial Inflammation and Apoptosis Through Inhibiting Endoplasmic Reticulum Stress Signaling
por: Yang, Yu-fan, et al.
Publicado: (2021)

Endoplasmic Reticulum Stress-Mediated Activation of p38 MAPK, Caspase-2 and Caspase-8 Leads to Abrin-Induced Apoptosis
por: Mishra, Ritu, et al.
Publicado: (2014)

Endoplasmic reticulum stress contributed to inflammatory bowel disease by activating p38 MAPK pathway
por: Long, Yan, et al.
Publicado: (2022)

Intracellular albumin overload elicits endoplasmic reticulum stress and PKC-delta/p38 MAPK pathway activation to induce podocyte apoptosis
por: Gonçalves, Guilherme Lopes, et al.
Publicado: (2018)

Dexmedetomidine Attenuates Myocardial Ischemia-Reperfusion Injury in Diabetes Mellitus by Inhibiting Endoplasmic Reticulum Stress
por: Li, Jinjie, et al.
Publicado: (2019)

FABP4 inhibitor BMS309403 protects against hypoxia‐induced H9c2 cardiomyocyte apoptosis through attenuating endoplasmic reticulum stress
por: Sun, Fuqiang, et al.
Publicado: (2020)

Up-regulation of Thioredoxin 1 by aerobic exercise training attenuates endoplasmic reticulum stress and cardiomyocyte apoptosis following myocardial infarction
por: Cai, Mengxin, et al.
Publicado: (2020)

Intermittent Hypoxia Induces Autophagy to Protect Cardiomyocytes From Endoplasmic Reticulum Stress and Apoptosis
por: Chang, Jui-Chih, et al.
Publicado: (2019)

Can dexmedetomidine reduce atrial fibrillation after cardiac surgery? A systematic review and meta-analysis
por: Zhu, Zhipeng, et al.
Publicado: (2018)

Does dexmedetomidine have an antiarrhythmic effect on cardiac patients? A meta-analysis of randomized controlled trials
por: Ling, Xiaoyan, et al.
Publicado: (2018)

Salidroside mitigates hypoxia/reoxygenation injury by alleviating endoplasmic reticulum stress-induced apoptosis in H9c2 cardiomyocytes
por: Sun, Meng-Yao, et al.
Publicado: (2018)

Melatonin attenuates cadmium-induced ovulatory dysfunction by suppressing endoplasmic reticulum stress and cell apoptosis
por: Yang, Qingling, et al.
Publicado: (2019)

p38 MAPK Facilitates Crosstalk Between Endoplasmic Reticulum Stress and IL-6 Release in the Intervertebral Disc
por: Krupkova, Olga, et al.
Publicado: (2018)

Neuritin Attenuates Neuronal Apoptosis Mediated by Endoplasmic Reticulum Stress In Vitro
por: Sun, Xiaokun, et al.
Publicado: (2018)

Calreticulin Translocation Aggravates Endoplasmic Reticulum Stress-associated Apoptosis during Cardiomyocyte Hypoxia/Reoxygenation
por: Xu, Fei-Fei, et al.
Publicado: (2015)

CRTH2 promotes endoplasmic reticulum stress‐induced cardiomyocyte apoptosis through m‐calpain
por: Zuo, Shengkai, et al.
Publicado: (2018)

Endoplasmic reticulum stress and apoptosis
por: Faitova, Jitka, et al.
Publicado: (2006)

Aconitine Induces TRPV2-Mediated Ca(2+) Influx through the p38 MAPK Signal and Promotes Cardiomyocyte Apoptosis
por: Yang, Chunai, et al.
Publicado: (2021)

Curcumin Nanoparticles Attenuate Lipotoxic Injury in Cardiomyocytes Through Autophagy and Endoplasmic Reticulum Stress Signaling Pathways
por: Gu, Yue, et al.
Publicado: (2021)

Downregulation of Cypher induces apoptosis in cardiomyocytes via Akt/p38 MAPK signaling pathway
por: Xuan, Tianming, et al.
Publicado: (2020)

Metformin inhibits testosterone-induced endoplasmic reticulum stress in ovarian granulosa cells via inactivation of p38 MAPK
por: Jin, Jiamin, et al.
Publicado: (2020)

Dexmedetomidine alleviates insulin resistance in hepatocytes by reducing endoplasmic reticulum stress
por: Liu, Fanfan, et al.
Publicado: (2019)

Biochanin A Alleviates Cerebral Ischemia/Reperfusion Injury by Suppressing Endoplasmic Reticulum Stress-Induced Apoptosis and p38MAPK Signaling Pathway In Vivo and In Vitro
por: Guo, Min-min, et al.
Publicado: (2021)

Glutamine Treatment Attenuates Endoplasmic Reticulum Stress and Apoptosis in TNBS-Induced Colitis
por: Crespo, Irene, et al.
Publicado: (2012)

Modulation of endoplasmic reticulum stress and cardiomyocyte apoptosis by mulberry leaf diet in experimental autoimmune myocarditis rats
por: Arumugam, Somasundaram, et al.
Publicado: (2012)

Rutin alleviates cardiomyocyte injury induced by high glucose through inhibiting apoptosis and endoplasmic reticulum stress
por: Wang, Jing, et al.
Publicado: (2021)

Irisin protects cardiomyocytes against hypoxia/reoxygenation injury via attenuating AMPK mediated endoplasmic reticulum stress
por: Yue, Rongchuan, et al.
Publicado: (2022)

AMP-Activated Protein Kinase Activation during Cardioplegia-Induced Hypoxia/Reoxygenation Injury Attenuates Cardiomyocytic Apoptosis via Reduction of Endoplasmic Reticulum Stress
por: Yeh, Chi-Hsiao, et al.
Publicado: (2010)

MicroRNA-194-5p Attenuates Doxorubicin-Induced Cardiomyocyte Apoptosis and Endoplasmic Reticulum Stress by Targeting P21-Activated Kinase 2
por: Fa, Hongge, et al.
Publicado: (2022)

TLR4 promoted endoplasmic reticulum stress induced inflammatory bowel disease via the activation of p38 MAPK pathway
por: Hu, Tian, et al.
Publicado: (2022)

Endoplasmic Reticulum Chaperon Tauroursodeoxycholic Acid Attenuates Aldosterone-Infused Renal Injury
por: Guo, Honglei, et al.
Publicado: (2016)

Klotho Suppresses Cardiomyocyte Apoptosis in Mice with Stress-Induced Cardiac Injury via Downregulation of Endoplasmic Reticulum Stress
por: Song, Shuang, et al.
Publicado: (2013)

Glucose fluctuation promotes cardiomyocyte apoptosis by triggering endoplasmic reticulum (ER) stress signaling pathway in vivo and in vitro
por: Wu, Li-Da, et al.
Publicado: (2022)

Grape seed proanthocyanidins protect against streptozotocin-induced diabetic nephropathy by attenuating endoplasmic reticulum stress-induced apoptosis
por: Gao, Zhaoli, et al.
Publicado: (2018)

Valproate attenuates diabetic nephropathy through inhibition of endoplasmic reticulum stress-induced apoptosis
por: SUN, XIN-YI, et al.
Publicado: (2016)

Autophagy decreases alveolar macrophage apoptosis by attenuating endoplasmic reticulum stress and oxidative stress
por: Fan, Tao, et al.
Publicado: (2016)

Chlorogenic acid attenuates liver apoptosis and inflammation in endoplasmic reticulum stress-induced mice
por: Moslehi, Azam, et al.
Publicado: (2023)

Attenuation of Endoplasmic Reticulum Stress Enhances Carvacrol-Induced Apoptosis in Osteosarcoma Cell Lines
por: Chiu, Kuan-Wei, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_fmakqkh9l3v73sj55qu6v6an9f