ZIKV viral proteins and their roles in virus-host interactions

The re-emergence of Zika virus (ZIKV) and its associated neonatal microcephaly and Guillain-Barré syndrome have led the World Health Organization to declare a global health emergency. Until today, many related studies have successively reported the role of various viral proteins of ZIKV in the proce...

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Autores principales: Guo, Moujian, Hui, Lixia, Nie, Yiwen, Tefsen, Boris, Wu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568452/
https://www.ncbi.nlm.nih.gov/pubmed/33068285
http://dx.doi.org/10.1007/s11427-020-1818-4
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author Guo, Moujian
Hui, Lixia
Nie, Yiwen
Tefsen, Boris
Wu, Ying
author_facet Guo, Moujian
Hui, Lixia
Nie, Yiwen
Tefsen, Boris
Wu, Ying
author_sort Guo, Moujian
collection PubMed
description The re-emergence of Zika virus (ZIKV) and its associated neonatal microcephaly and Guillain-Barré syndrome have led the World Health Organization to declare a global health emergency. Until today, many related studies have successively reported the role of various viral proteins of ZIKV in the process of ZIKV infection and pathogenicity. These studies have provided significant insights for the treatment and prevention of ZIKV infection. Here we review the current research advances in the functional characterization of the interactions between each ZIKV viral protein and its host factors.
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spelling pubmed-75684522020-10-19 ZIKV viral proteins and their roles in virus-host interactions Guo, Moujian Hui, Lixia Nie, Yiwen Tefsen, Boris Wu, Ying Sci China Life Sci Review The re-emergence of Zika virus (ZIKV) and its associated neonatal microcephaly and Guillain-Barré syndrome have led the World Health Organization to declare a global health emergency. Until today, many related studies have successively reported the role of various viral proteins of ZIKV in the process of ZIKV infection and pathogenicity. These studies have provided significant insights for the treatment and prevention of ZIKV infection. Here we review the current research advances in the functional characterization of the interactions between each ZIKV viral protein and its host factors. Science China Press 2020-10-14 2021 /pmc/articles/PMC7568452/ /pubmed/33068285 http://dx.doi.org/10.1007/s11427-020-1818-4 Text en © Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Review
Guo, Moujian
Hui, Lixia
Nie, Yiwen
Tefsen, Boris
Wu, Ying
ZIKV viral proteins and their roles in virus-host interactions
title ZIKV viral proteins and their roles in virus-host interactions
title_full ZIKV viral proteins and their roles in virus-host interactions
title_fullStr ZIKV viral proteins and their roles in virus-host interactions
title_full_unstemmed ZIKV viral proteins and their roles in virus-host interactions
title_short ZIKV viral proteins and their roles in virus-host interactions
title_sort zikv viral proteins and their roles in virus-host interactions
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568452/
https://www.ncbi.nlm.nih.gov/pubmed/33068285
http://dx.doi.org/10.1007/s11427-020-1818-4
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