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Hepatocytes trap and silence coxsackieviruses, protecting against systemic disease in mice

Previous research suggests that hepatocytes catabolize chemical toxins but do not remove microbial agents, which are filtered out by other liver cells (Kupffer cells and endothelial cells). Here we show that, contrary to current understanding, hepatocytes trap and rapidly silence type B coxsackievir...

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Detalles Bibliográficos
Autores principales: Kimura, Taishi, Flynn, Claudia T., Whitton, J. Lindsay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568585/
https://www.ncbi.nlm.nih.gov/pubmed/33067530
http://dx.doi.org/10.1038/s42003-020-01303-7