Efficacy and Resistance of ALK Inhibitors in Two Inflammatory Myofibroblastic Tumor Patients with ALK Fusions Assessed by Whole Exome and RNA Sequencing

We report two inflammatory myofibroblastic tumor (IMT) patients with ALK fusions (RRBP-ALK and TNS1-ALK, respectively). They both received tumor resection surgery and treatment with ALK inhibitors crizotinib followed by alectinib, and upon receiving each of the drugs, showed a brief response, then e...

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Detalles Bibliográficos
Autores principales: Zhang, Chenlu, Wang, Zhiming, Zhuang, Rongyuan, Guo, Xi, Feng, Yi, Shen, Feng, Liu, Wenshuai, Zhang, Yong, Tong, Hanxing, Sun, Wending, Liu, Jun, Wang, Guan, Dai, Chun, Lu, Weiqi, Zhou, Yuhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568619/
https://www.ncbi.nlm.nih.gov/pubmed/33116613
http://dx.doi.org/10.2147/OTT.S270481

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