A Trypanosoma brucei ORFeome-Based Gain-of-Function Library Identifies Genes That Promote Survival during Melarsoprol Treatment

Trypanosoma brucei is an early branching protozoan parasite that causes human and animal African trypanosomiasis. Forward genetics approaches are powerful tools for uncovering novel aspects of trypanosomatid biology, pathogenesis, and therapeutic approaches against trypanosomiasis. Here, we have gen...

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Detalles Bibliográficos
Autores principales: Carter, McKenzie, Gomez, Stephanie, Gritz, Sam, Larson, Stephen, Silva-Herzog, Eugenia, Kim, Hee-Sook, Schulz, Danae, Hovel-Miner, Galadriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568655/
https://www.ncbi.nlm.nih.gov/pubmed/33028684
http://dx.doi.org/10.1128/mSphere.00769-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568655/
https://www.ncbi.nlm.nih.gov/pubmed/33028684
http://dx.doi.org/10.1128/mSphere.00769-20

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