Cargando…

Clarithromycin-Loaded Ocular Chitosan Nanoparticle: Formulation, Optimization, Characterization, Ocular Irritation, and Antimicrobial Activity

PURPOSE: The topically administered drugs through conventional delivery systems have low bioavailability. Henceforth, the present study was designed to prepare and optimize clarithromycin (CTM)-loaded chitosan nanoparticles (CHNPs) to demonstrate the efficacy against microorganisms. METHODS: Clarith...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bin-Jumah, May, Gilani, Sadaf Jamal, Jahangir, Mohammed Asadullah, Zafar, Ameeduzzafar, Alshehri, Sultan, Yasir, Mohd, Kala, Chandra, Taleuzzaman, Mohamad, Imam, Syed Sarim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568680/ https://www.ncbi.nlm.nih.gov/pubmed/33116505 http://dx.doi.org/10.2147/IJN.S269004

Ejemplares similares

Formulation of Miconazole-Loaded Chitosan–Carbopol Vesicular Gel: Optimization to In Vitro Characterization, Irritation, and Antifungal Assessment
por: Imam, Syed Sarim, et al.
Publicado: (2023)

Formulation and Evaluation of Nano Lipid Carrier-Based Ocular Gel System: Optimization to Antibacterial Activity
por: Gilani, Sadaf Jamal, et al.
Publicado: (2022)

Formulation of Isopropyl Isothiocyanate Loaded Nano Vesicles Delivery Systems: In Vitro Characterization and In Vivo Assessment
por: Kala, Chandra, et al.
Publicado: (2022)

Stimulus Responsive Ocular Gentamycin-Ferrying Chitosan Nanoparticles Hydrogel: Formulation Optimization, Ocular Safety and Antibacterial Assessment
por: Alruwaili, Nabil K, et al.
Publicado: (2020)

Thymoquinone-entrapped chitosan-modified nanoparticles: formulation optimization to preclinical bioavailability assessments
por: Rahat, Iqra, et al.
Publicado: (2021)

Formulation of Piperine–Chitosan-Coated Liposomes: Characterization and In Vitro Cytotoxic Evaluation
por: Imam, Syed Sarim, et al.
Publicado: (2021)

Formulation and Optimization of Butenafine-Loaded Topical Nano Lipid Carrier-Based Gel: Characterization, Irritation Study, and Anti-Fungal Activity
por: Mahdi, Wael A., et al.
Publicado: (2021)

Harnessing Lipid Polymer Hybrid Nanoparticles for Enhanced Oral Bioavailability of Thymoquinone: In Vitro and In Vivo Assessments
por: Imam, Syed Sarim, et al.
Publicado: (2022)

Recent Advancement in Chitosan-Based Nanoparticles for Improved Oral Bioavailability and Bioactivity of Phytochemicals: Challenges and Perspectives
por: Imam, Syed Sarim, et al.
Publicado: (2021)

Formulation and Optimization of Alogliptin-Loaded Polymeric Nanoparticles: In Vitro to In Vivo Assessment
por: Mohanty, Dibyalochan, et al.
Publicado: (2022)

ZnO Nanoparticles of Rubia cordifolia Extract Formulation Developed and Optimized with QbD Application, Considering Ex Vivo Skin Permeation, Antimicrobial and Antioxidant Properties
por: Kaur, Jasmeet, et al.
Publicado: (2022)

Formulation and evaluation of butenafine loaded PLGA-nanoparticulate laden chitosan nano gel
por: Alshehri, Sultan, et al.
Publicado: (2021)

Formulation of Genistein-HP β Cyclodextrin-Poloxamer 188 Ternary Inclusion Complex: Solubility to Cytotoxicity Assessment
por: Zafar, Ameeduzzafar, et al.
Publicado: (2021)

Formulation and Evaluation of Topical Nano-Lipid-Based Delivery of Butenafine: In Vitro Characterization and Antifungal Activity
por: Zafar, Ameeduzzafar, et al.
Publicado: (2022)

Formulation and Evaluation of Moxifloxacin Loaded Bilosomes In-Situ Gel: Optimization to Antibacterial Evaluation
por: Zafar, Ameeduzzafar, et al.
Publicado: (2022)

Development and Optimization of Nanolipid-Based Formulation of Diclofenac Sodium: In Vitro Characterization and Preclinical Evaluation
por: Zafar, Ameeduzzafar, et al.
Publicado: (2022)

Formulation of Self-Nanoemulsifying Drug Delivery System of Cephalexin: Physiochemical Characterization and Antibacterial Evaluation
por: Zafar, Ameeduzzafar, et al.
Publicado: (2022)

Formulation of Chitosan-Coated Apigenin Bilosomes: In Vitro Characterization, Antimicrobial and Cytotoxicity Assessment
por: Imam, Syed Sarim, et al.
Publicado: (2022)

Development, In-Vitro Characterization and Preclinical Evaluation of Esomeprazole-Encapsulated Proniosomal Formulation for the Enhancement of Anti-Ulcer Activity
por: Mohanty, Dibyalochan, et al.
Publicado: (2022)

Pathobiological Relationship of Excessive Dietary Intake of Choline/L-Carnitine: A TMAO Precursor-Associated Aggravation in Heart Failure in Sarcopenic Patients
por: Bin-Jumah, May Nasser, et al.
Publicado: (2021)

Bioactive Apigenin loaded oral nano bilosomes: Formulation optimization to preclinical assessment
por: Zafar, Ameeduzzafar, et al.
Publicado: (2021)

In vitro alternatives for ocular irritation.
por: Curren, R D, et al.
Publicado: (1998)

Chitosan and its Derivatives for Ocular Delivery Formulations: Recent Advances and Developments
por: Zamboulis, Alexandra, et al.
Publicado: (2020)

Development and evaluation of luteolin loaded pegylated bilosome: optimization, in vitro characterization, and cytotoxicity study
por: Zafar, Ameeduzzafar, et al.
Publicado: (2021)

Stimulus Responsive Ocular Gentamycin-Ferrying Chitosan Nanoparticles Hydrogel: Formulation Optimization, Ocular Safety and Antibacterial Assessment [Retraction]
Publicado: (2023)

Rosinidin Flavonoid Ameliorates Hyperglycemia, Lipid Pathways and Proinflammatory Cytokines in Streptozotocin-Induced Diabetic Rats
por: Gilani, Sadaf Jamal, et al.
Publicado: (2022)

Antiamnesic Potential of Malvidin on Aluminum Chloride Activated by the Free Radical Scavenging Property
por: Gilani, Sadaf Jamal, et al.
Publicado: (2022)

Preparation of NLCs-Based Topical Erythromycin Gel: In Vitro Characterization and Antibacterial Assessment
por: Zafar, Ameeduzzafar, et al.
Publicado: (2022)

Development and Optimization of Hybrid Polymeric Nanoparticles of Apigenin: Physicochemical Characterization, Antioxidant Activity and Cytotoxicity Evaluation
por: Zafar, Ameeduzzafar, et al.
Publicado: (2022)

Development of Ciprofloxacin-Loaded Bilosomes In-Situ Gel for Ocular Delivery: Optimization, In-Vitro Characterization, Ex-Vivo Permeation, and Antimicrobial Study
por: Alsaidan, Omar Awad, et al.
Publicado: (2022)

Protective Effect of Fustin Against Ethanol-Activated Gastric Ulcer via Downregulation of Biochemical Parameters in Rats
por: Gilani, Sadaf Jamal, et al.
Publicado: (2022)

Face Mask-Associated Ocular Irritation and Dryness
por: Moshirfar, Majid, et al.
Publicado: (2020)

Formulation development, in vitro and in vivo evaluation of chitosan engineered nanoparticles for ocular delivery of insulin
por: Rathore, Priyanka, et al.
Publicado: (2020)

Clarithromycin Solid Lipid Nanoparticles for Topical Ocular Therapy: Optimization, Evaluation, and In Vivo Studies
por: Nair, Anroop B., et al.
Publicado: (2021)

Improvement of Ocular Efficacy of Levofloxacin by Bioadhesive Chitosan Coated PLGA Nanoparticles: Box-behnken Design, In-vitro Characterization, Antibacterial Evaluation and Scintigraphy Study
por: Ameeduzzafar,, et al.
Publicado: (2020)

Rosinidin Attenuates Lipopolysaccharide-Induced Memory Impairment in Rats: Possible Mechanisms of Action Include Antioxidant and Anti-Inflammatory Effects
por: Alshehri, Sultan, et al.
Publicado: (2021)

Formulation and Evaluation of Apigenin-Loaded Hybrid Nanoparticles
por: Kazmi, Imran, et al.
Publicado: (2022)

Formulation of Silymarin-β Cyclodextrin-TPGS Inclusion Complex: Physicochemical Characterization, Molecular Docking, and Cell Viability Assessment against Breast Cancer Cell Lines
por: Imam, Syed Sarim, et al.
Publicado: (2023)

Cannabinoid-Based Ocular Therapies and Formulations
por: Saraiva, Sofia M., et al.
Publicado: (2023)

Formulation and Evaluation of Supramolecular Food-Grade Piperine HP β CD and TPGS Complex: Dissolution, Physicochemical Characterization, Molecular Docking, In Vitro Antioxidant Activity, and Antimicrobial Assessment
por: Imam, Syed Sarim, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oas14te5eio7ljbte00n7u3gvd