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Exploratory open-label clinical study to determine the S-588410 cancer peptide vaccine-induced tumor-infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients

Cancer vaccines induce cancer-specific T-cells capable of eradicating cancer cells. The impact of cancer peptide vaccines (CPV) on the tumor microenvironment (TME) remains unclear. S-588410 is a CPV comprising five human leukocyte antigen (HLA)-A*24:02-restricted peptides derived from five cancer te...

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Detalles Bibliográficos
Autores principales: Daiko, H., Marafioti, T., Fujiwara, T., Shirakawa, Y., Nakatsura, T., Kato, K., Puccio, I., Hikichi, T., Yoshimura, S., Nakagawa, T., Furukawa, M., Stoeber, K., Nagira, M., Ide, N., Kojima, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568713/
https://www.ncbi.nlm.nih.gov/pubmed/32500232
http://dx.doi.org/10.1007/s00262-020-02619-3