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Exploratory open-label clinical study to determine the S-588410 cancer peptide vaccine-induced tumor-infiltrating lymphocytes and changes in the tumor microenvironment in esophageal cancer patients
Cancer vaccines induce cancer-specific T-cells capable of eradicating cancer cells. The impact of cancer peptide vaccines (CPV) on the tumor microenvironment (TME) remains unclear. S-588410 is a CPV comprising five human leukocyte antigen (HLA)-A*24:02-restricted peptides derived from five cancer te...
Autores principales: | Daiko, H., Marafioti, T., Fujiwara, T., Shirakawa, Y., Nakatsura, T., Kato, K., Puccio, I., Hikichi, T., Yoshimura, S., Nakagawa, T., Furukawa, M., Stoeber, K., Nagira, M., Ide, N., Kojima, T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568713/ https://www.ncbi.nlm.nih.gov/pubmed/32500232 http://dx.doi.org/10.1007/s00262-020-02619-3 |
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