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The histone H2B ubiquitin ligase RNF40 is required for HER2-driven mammary tumorigenesis
The HER2-positive breast cancer subtype (HER2(+)-BC) displays a particularly aggressive behavior. Anti-HER2 therapies have significantly improved the survival of patients with HER2(+)-BC. However, a large number of patients become refractory to current targeted therapies, necessitating the developme...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568723/ https://www.ncbi.nlm.nih.gov/pubmed/33070155 http://dx.doi.org/10.1038/s41419-020-03081-w |