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Micro-environmental cross-talk in an organotypic human melanoma-in-skin model directs M2-like monocyte differentiation via IL-10

Preclinical assessment of novel therapies to fight cancer requires models that reflect the human physiology and immune response. Here, we established an in vitro three-dimensional (3D) reconstructed organotypic human melanoma-in-skin (Mel-RhS) model to investigate cellular and molecular features of...

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Detalles Bibliográficos
Autores principales:	Michielon, Elisabetta, López González, Marta, Burm, Judith L. A., Waaijman, Taco, Jordanova, Ekaterina S., de Gruijl, Tanja D., Gibbs, Susan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568725/ https://www.ncbi.nlm.nih.gov/pubmed/32507967 http://dx.doi.org/10.1007/s00262-020-02626-4

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