Cargando…
Ginsenoside Rg1 Alleviates Podocyte Injury Induced by Hyperlipidemia via Targeting the mTOR/NF-κB/NLRP3 Axis
BACKGROUND: Podocyte injury plays an important role in diabetic nephropathy (DN). The aim of this study was to determine the potential therapeutic effects of the ginsenoside Rg1 on hyperlipidemia-stressed podocytes and elucidate the underlying mechanisms. METHODS: In vitro and in vivo models of DN w...
Autores principales: | Wang, Tao, Gao, Yanbin, Yue, Rongchuan, Wang, Xiaolei, Shi, Yimin, Xu, Jiayi, Wu, Bingjie, Li, Yimeng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568787/ https://www.ncbi.nlm.nih.gov/pubmed/33133213 http://dx.doi.org/10.1155/2020/2735714 |
Ejemplares similares
-
Ginsenoside Rg1 Alleviates Podocyte EMT Passage by Regulating AKT/GSK3 β/β-Catenin Pathway by Restoring Autophagic Activity
por: Shi, Yimin, et al.
Publicado: (2020) -
Calpain-10 drives podocyte apoptosis and renal injury in diabetic nephropathy
por: Wang, Tao, et al.
Publicado: (2019) -
Astragaloside IV inhibits glucose-induced epithelial-mesenchymal transition of podocytes through autophagy enhancement via the SIRT–NF-κB p65 axis
por: Wang, Xiaolei, et al.
Publicado: (2019) -
Ginsenoside Rg1 Ameliorates Pancreatic Injuries via the AMPK/mTOR Pathway in vivo and in vitro
por: Chen, Jin, et al.
Publicado: (2023) -
Ginsenoside Rg1 alleviates acute liver injury through the induction of autophagy and suppressing NF-κB/NLRP3 inflammasome signaling pathway
por: Zhao, Jinqiu, et al.
Publicado: (2021)