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Anabolic Steroid Use and Aortic Dissection in Athletes: A Case Series

The use of anabolic steroids in supraphysiologic doses has grown in the last decade as doping drugs in athletes. The high dose of anabolic-androgenic steroids (AAS) causes cardiomyopathy, hypertension, thrombosis, myocardial infarction (MI), weakness of connective tissue, and its sequelae such as te...

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Autores principales: Heydari, Aghigh, Asadmobini, Atefeh, Sabzi, Feridoun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OMJ 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568822/
https://www.ncbi.nlm.nih.gov/pubmed/33083037
http://dx.doi.org/10.5001/omj.2020.120
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author Heydari, Aghigh
Asadmobini, Atefeh
Sabzi, Feridoun
author_facet Heydari, Aghigh
Asadmobini, Atefeh
Sabzi, Feridoun
author_sort Heydari, Aghigh
collection PubMed
description The use of anabolic steroids in supraphysiologic doses has grown in the last decade as doping drugs in athletes. The high dose of anabolic-androgenic steroids (AAS) causes cardiomyopathy, hypertension, thrombosis, myocardial infarction (MI), weakness of connective tissue, and its sequelae such as tendon injury and aortic dissection. Dissection of the ascending aorta is an uncommon injury that has been recognized with increasing frequency in bodybuilders in recent years. It has been proposed that such cases commonly accompany the weakening of connective tissue and must be actively evaluated in the presence of anabolic steroid usage. We present a case series of isolated ascending aorta dissection in athletes who were bodybuilders. All cases were evaluated by transthoracic echocardiography (TTE) and laboratory exams. These cases also served as a reminder of the risks of ascending aorta dissection with AAS, especially in strength athletes who place high demands on their musculoskeletal structures. The results of the current study suggested that anabolic steroid abuse may be associated with detrimental effects on the myocardium represented as cardiomyopathy or atherosclerotic changes in the coronary artery as MI. These findings also strongly suggest that anabolic steroid treatment predisposes the individual to aortic dissection, especially when the patients are exercised.
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spelling pubmed-75688222020-10-19 Anabolic Steroid Use and Aortic Dissection in Athletes: A Case Series Heydari, Aghigh Asadmobini, Atefeh Sabzi, Feridoun Oman Med J Case Report The use of anabolic steroids in supraphysiologic doses has grown in the last decade as doping drugs in athletes. The high dose of anabolic-androgenic steroids (AAS) causes cardiomyopathy, hypertension, thrombosis, myocardial infarction (MI), weakness of connective tissue, and its sequelae such as tendon injury and aortic dissection. Dissection of the ascending aorta is an uncommon injury that has been recognized with increasing frequency in bodybuilders in recent years. It has been proposed that such cases commonly accompany the weakening of connective tissue and must be actively evaluated in the presence of anabolic steroid usage. We present a case series of isolated ascending aorta dissection in athletes who were bodybuilders. All cases were evaluated by transthoracic echocardiography (TTE) and laboratory exams. These cases also served as a reminder of the risks of ascending aorta dissection with AAS, especially in strength athletes who place high demands on their musculoskeletal structures. The results of the current study suggested that anabolic steroid abuse may be associated with detrimental effects on the myocardium represented as cardiomyopathy or atherosclerotic changes in the coronary artery as MI. These findings also strongly suggest that anabolic steroid treatment predisposes the individual to aortic dissection, especially when the patients are exercised. OMJ 2020-09-30 /pmc/articles/PMC7568822/ /pubmed/33083037 http://dx.doi.org/10.5001/omj.2020.120 Text en The OMJ is Published Bimonthly and Copyrighted 2020 by the OMSB. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial (CC BY-NC) 4.0 License. http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Case Report
Heydari, Aghigh
Asadmobini, Atefeh
Sabzi, Feridoun
Anabolic Steroid Use and Aortic Dissection in Athletes: A Case Series
title Anabolic Steroid Use and Aortic Dissection in Athletes: A Case Series
title_full Anabolic Steroid Use and Aortic Dissection in Athletes: A Case Series
title_fullStr Anabolic Steroid Use and Aortic Dissection in Athletes: A Case Series
title_full_unstemmed Anabolic Steroid Use and Aortic Dissection in Athletes: A Case Series
title_short Anabolic Steroid Use and Aortic Dissection in Athletes: A Case Series
title_sort anabolic steroid use and aortic dissection in athletes: a case series
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7568822/
https://www.ncbi.nlm.nih.gov/pubmed/33083037
http://dx.doi.org/10.5001/omj.2020.120
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